Claire Williams
PhD
Senior Researcher
Claire Williams joined HERC in August 2019 as a Senior Researcher focused on cardiovascular disease modelling. She works on lifetime risk projections of cardiovascular events and associated healthcare costs for individual patient profiles based on large randomised control trials (REVEAL, CTT).
Immediately prior to joining HERC, Claire focused on cost-effectiveness modelling and Value of Information analysis to evaluate the use of wound dressings to reduce surgical site infections.
Claire brings with her extensive experience as a medical statistician in both the NHS and academia. She completed her PhD exploring the potential of the continuous-time approach to multi-state modelling in an epidemiological and health economics context within the Health Economics and Health Technology Assessment research group at the University of Glasgow.
She has a particular ongoing interest in the use of state transition modelling and its implementation in R and in comparing them to other methods of clinical- and cost-effectiveness analysis.
Key publications
Estimating Costs Associated with Disease Model States Using Generalized Linear Models: A Tutorial.
Journal article
Zhou J. et al, (2024), Pharmacoeconomics, 42, 261 - 273
Impact of new cardiovascular events on quality of life and hospital costs in people with cardiovascular disease in the UK and US
Journal article
MIHAYLOVA B. et al, (2023), Journal of the American Heart Association
P70 Calibrating Cardiovascular Disease Policy Model Using Large Cohort Data
Presentation
Wu R. et al, (2022), Value in Health, 25, S16 - S16
P55 Excess Annual Hospital Costs Due to Cardiovascular Events in a Contemporary UK Population to Inform Health Technology Assessments
Presentation
Zhou J. et al, (2022), Value in Health, 25, S12 - S12
Cost-effectiveness Analysis in R Using a Multi-state Modeling Survival Analysis Framework: A Tutorial.
Journal article
Williams C. et al, (2017), Med Decis Making, 37, 340 - 352
Recent publications
Lifetime effects and cost-effectiveness of statin therapy for older people in the United Kingdom: a modelling study
Journal article
MIHAYLOVA B. et al, (2024), Heart
Estimating Costs Associated with Disease Model States Using Generalized Linear Models: A Tutorial.
Journal article
Zhou J. et al, (2024), Pharmacoeconomics, 42, 261 - 273
Lifetime effects and cost-effectiveness of standard and higher-intensity statin therapy across population categories in the UK: a microsimulation modelling study
Journal article
MIHAYLOVA B. et al, (2024), The Lancet Regional Health - Europe
Assessing long-term effectiveness and cost-effectiveness of statin therapy in the UK: a modelling study using individual participant datasets
Journal article
MIHAYLOVA B. et al, (2024), NIHR Journals Library
Long-term cardiovascular risks and statin treatment impact on socioeconomic inequalities: microsimulation model
Journal article
Wu R. et al, (2023), British Journal of General Practice

