Professor Sasha Shepperd

Contact information

Email
sasha.shepperd@ndph.ox.ac.uk

Websites

Ethnicity and breast cancer
Funded by the Prevention and Population Research Committee at Cancer Research UK (CI Toral Gathani)
Old Age Neuroscience and the ORCHARD portfolio
Nuffield Department of Clinical Neurosciences

Sasha Shepperd

BA, MSc, DPhil

Professor of Health Services Research & Interim Director of HERC

Co-lead of the Applied Health Research Unit
Oxford Population Health lead for equality, diversity and inclusion

Sasha’s research uses epidemiological methods, randomised trials and evidence synthesis to answer pressing health service/systems questions, with a focus on population ageing. Sasha was the chief investigator of a NIHR funded multi-site randomised trial of Hospital at Home vs hospital admission that was awarded the BGS Dhole-Eddlestone Memorial prize in 2023 and contributed to the evidence supporting NHS England’s virtual ward programme. Currently her research includes understanding the impact of inequalities that drive the need for social care by an older population, she is a co-investigator on CRUK funded research (led by Toral Gathani) on barriers and facilitators to the early diagnosis of breast cancer in ethnic minority women and a co-lead for the Cochrane Thematic Group: People, Health Systems and Public Health.

After an undergraduate degree in psychology from the University of Vermont, Sasha completed a master's at the Harvard School of Public Health and a DPhil at the University of Oxford.

Key publications

Economic Evaluations of Medication Safety Interventions in Primary and Long-Term Care: A Systematic Review.

Amritlal ST. et al, (2026), Pharmacoeconomics, 44, 299 - 316

Optimising the monitoring and management of raised blood pressure including proteinuria testing during pregnancy: the BUMP research programme including 2 RCTs

McManus RJ. et al, (2026), Programme Grants for Applied Research, 1 - 50

Economic evaluations in the palliative and end-of-life care settings: A systematic review of existing evidence, methods and quality.

Fischer C. et al, (2026), Palliat Med

Follow-up of suspected child maltreatment cases treated at a tertiary child protection service facility.

Mora-Theuer EA. et al, (2026), Eur J Pediatr, 185

Towards a Multi-sectoral Approach to Population Health: A Scoping Review of Cross-sectoral Evaluations of Health Interventions.

Koleva-Kolarova R. et al, (2026), Appl Health Econ Health Policy

Is liquid biopsy a cost-effective method to diagnose Burkitt Lymphoma in children and young adults? A health economic evaluation in Tanzania.

Jiang J. et al, (2026), BMC Med

Influence of stage at cancer diagnosis on NHS hospital care costs in England: a national, retrospective, population-based cohort study using individual patient-level data.

Pearson C. et al, (2026), Lancet Oncol

Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials

REITH C. et al, (2026), The Lancet

Substantial variation in the cost of blood group and save and crossmatch: a systematic review

Fabiano G. et al, (2026), British Journal of Haematology

Improving Collaborative Engagement in Health State Valuation: A Scoping Review of Current Practices and Emerging Recommendations.

Powell PA. et al, (2026), Pharmacoeconomics, 44, 141 - 163

Supporting women with adherence to adjuvant endocrine therapy (SWEET): feasibility study of the HT&Me intervention.

McGeagh L. et al, (2026), Eur J Oncol Nurs, 80

Cost-effectiveness of pramipexole augmentation for acute phase and maintenance therapy of treatment-resistant depression compared to placebo augmentation: economic evaluation of the PAX-D randomised controlled trial.

Łaszewska A. et al, (2026), Lancet Reg Health Eur, 61

Theoretically Universal, Practically Unequal: Socio-Economic Inequalities in Healthcare Access for Long Covid-19 Patients in Austria.

Gamillscheg-Müllner P. et al, (2026), Health Expect, 29

On "Inequality in COVID-19 vaccine acceptance and uptake".

Abel ZDV. et al, (2026), Health Policy, 164

Gabapentin as an adjunct to multimodal pain regimens in surgical patients: the GAP placebo-controlled RCT and economic evaluation.

Baos S. et al, (2026), Health Technol Assess, 30, 1 - 144

Modelled impact of a multi-cancer early detection screening programme on the demand for diagnostics in England

Martin J. et al, (2026), British Journal of Cancer

Improving outcomes in adult patients who self-harm-evaluating a brief psychological intervention in emergency departments (ASSURED): protocol of a randomised controlled clinical trial.

McCabe R. et al, (2026), Trials

Estimating the Potential Impact of the 2024 UK Salt Reduction Targets on Cardiovascular Health Outcomes and Health Care Costs in Adults: A Modeling Study

Bandy L., (2026), Hypertension

Corrigendum to "Accuracy of online surveys in predicting COVID-19 vaccine uptake and demand: A cohort study investigating vaccine sentiments and switching in 13 countries from 2020 to 2022" [Vaccines 62 (2025) 127450].

Abel ZDV. et al, (2026), Vaccine, 71

EQ-5D vision bolt-on in macular degeneration: Associations with visual measures and effect on utility differences and cost-effectiveness of stereotactic radiotherapy

Zhu X. et al, (2026), Health and Quality of Life Outcomes

Translation, cross-cultural adaptation, and validation of the Caregiver Indirect and Informal Care Cost Assessment Questionnaire for end-of-life care into Spanish.

Lamfre LS. et al, (2026), Palliat Support Care, 24

Avoiding routine gastric residual volume measurement in neonatal critical care (the neoGASTRIC trial): study protocol for a multi-centre, unblinded, randomised, controlled trial

NUTHALL E. et al, (2026), Trials

Parent-led CBT delivered via online and telephone support alongside usual school practice versus usual school practice only for young children identified as at-risk for anxiety disorders through screening in schools: a cluster randomised controlled trial

REARDON T., (2026), Journal of Child Psychology and Psychiatry

Association between health literacy and reproductive health knowledge and behavior : A cross-sectional survey among women of reproductive age in Vienna.

Rottjakob P. et al, (2026), Wien Klin Wochenschr

Correction: Preferences for multi-cancer tests (MCTs) in primary care: discrete choice experiments of general practitioners and the general public in England.

Buckell J. et al, (2026), Br J Cancer, 134, 175 - 176

Roux-en-Y gastric bypass, adjustable gastric banding or sleeve gastrectomy for severe obesity: The By-Band-Sleeve randomised controlled trial.

(2026), Health Technol Assess, 30, 1 - 224

Correspondence on "Parents' perceptions of the utility of genetic testing in the NICU" by Callahan et al.

Sansom SL. et al, (2026), Genet Med, 28

Comparing Adolescent and Adult Preferences for EQ-5D-Y-3L Health States in Hong Kong.

Wang K. et al, (2026), Value Health, 29, 139 - 148

Factors associated with hospitalisations, emergency visits and related costs in inflammatory bowel disease: insights from the TrueColours-IBD digital monitoring programme in Oxford

Fierens L. et al, (2026), JOURNAL OF CROHNS & COLITIS, 20

Trial protocol: DOLFIN trial: Developmental Outcomes of Long-term Feed Supplementation in Neonates-A UK multicentre, blinded, stratified, randomised controlled trial.

Andrew MJ. et al, (2025), Trials, 26

Economic effects for citizens and the government of a country-level tobacco endgame strategy: a modelling study.

Ait Ouakrim D. et al, (2025), Tob Control, 34, e9 - e16

The HERC Database of Mapping Studies: a 2025 update of a live systematic review of studies predicting EQ-5D from other patient-reported outcome measures

Mallon K. et al, (2025), Value in Health, 28, s534 - s535

Patient-reported harm from NHS treatment or care, or the lack of access to care: a cross-sectional survey of general population prevalence, impact and responses.

Crocker H. et al, (2025), BMJ Qual Saf, 35, 30 - 42

Cost-effectiveness of pramipexole in addition to mood stabilisers for patients with treatment-resistant bipolar depression: Economic evaluation of the PAX-BD randomised controlled trial.

Berger M. et al, (2025), J Affect Disord, 391

Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study.

Little M. et al, (2025), Eur Urol Focus

Mapping the benefits and harms of antenatal and newborn screening programmes

HINTON L. et al, (2025), SSM: Qualitative Research in Health

Quality of life of primary caregivers by severity and control of children's asthma: a systematic review and meta-analysis.

Tomini F. et al, (2025), Qual Life Res, 34, 3425 - 3445

Prevalence of cognitive morbidity including delirium in 51,202 emergency hospital admissions across 29 medical and surgical specialties in ORCHARD-EPR: a cross-sectional study.

Boucher EL. et al, (2025), EClinicalMedicine, 90

Proactive Integrated Consultation-Liaison Psychiatry for older medical inpatients: The HOME Study RCT of its effectiveness and cost-effectiveness.

Sharpe M. et al, (2025), Health Soc Care Deliv Res, 13, 1 - 85

Barriers, facilitators, and the role of central coordination: understanding long COVID-19 healthcare access in a universal healthcare system.

Gamillscheg-Müllner P. et al, (2025), Arch Public Health, 83

Improving outcomeS for Women diagnosed with early breast cancer through adhErence to adjuvant Endocrine Therapy (SWEET): study protocol for a pragmatic Randomised Control Trial of a patient-centred intervention to improve adherence to endocrine therapy in early breast cancer

Mcgeagh L. et al, (2025), Trials

2025 ESC/EACTS Guidelines for the management of valvular heart disease.

Praz F. et al, (2025), Eur Heart J, 46, 4635 - 4736

2025 ESC Guidelines for the management of cardiovascular disease and pregnancy.

De Backer J. et al, (2025), Eur Heart J, 46, 4462 - 4568

SurfON Trial: Study Protocol for a multicentre, open-label, randomised controlled trial of early surfactant therapy versus expectant management in late preterm and early term infants with respiratory distress.

Boyle EM. et al, (2025), Trials

Long-term effectiveness and cost-effectiveness of testing for alemtuzumab antidrug antibodies to guide treatment in multiple sclerosis: a modelling study.

Jamieson T. et al, (2025), Eur J Health Econ

Optimising antibiotic “review and revise” in acute/general medical inpatients: the Antibiotic Review Kit in Hospitals (ARK-Hospital) research programme including a stepped-wedge cluster-randomised trial

Llewelyn MJ. et al, (2025), NIHR Journals Library

Validation and cost-effectiveness of an mHealth tool for cognitive impairment detection in Peru: protocol for the IMPACT Salud observational study.

Cardenas MK. et al, (2025), BMJ Open, 15

HERC database of mapping studies, Version 10.0

DAKIN H. et al, (2025)

2025 Focused Update of the 2019 ESC/EAS Guidelines for the management of dyslipidaemias.

Mach F. et al, (2025), Eur Heart J, 46, 4359 - 4378

2025 ESC Clinical Consensus Statement on mental health and cardiovascular disease: developed under the auspices of the ESC Clinical Practice Guidelines Committee.

Bueno H. et al, (2025), Eur Heart J, 46, 4156 - 4225

Cost-effectiveness of CA125- and age-informed risk-based triage for ovarian cancer detection in primary care.

Wu R. et al, (2025), Br J Cancer, 133, 1492 - 1500

The Risk-Benefit Balance of Oral Corticosteroid Treatment for Asthma Attacks: A Discrete Choice Experiment of Patients and Healthcare Professionals in the UK and New Zealand.

Howell I. et al, (2025), Respirology, 30, 1035 - 1045

International Variation in Case Fatality After Major Coronary or Cerebrovascular Events in Individuals With Type 2 Diabetes: Evidence From ADVANCE, TECOS, and EXSCEL.

Clarke PM. et al, (2025), Diabetes Care, 48, 1925 - 1931

A Break from the Norm? Parametric Representations of Preference Heterogeneity for Discrete Choice Models in Health.

Buckell J. et al, (2025), Med Decis Making, 45, 987 - 1001

Climate change and mental health: announcing a new Lancet Psychiatry Commission.

Brandt L. et al, (2025), Lancet Psychiatry, 12, 811 - 813

Recent publications

Prevalence of cognitive morbidity including delirium in 51,202 emergency hospital admissions across 29 medical and surgical specialties in ORCHARD-EPR: a cross-sectional study.

Boucher EL. et al, (2025), EClinicalMedicine, 90

Proactive Integrated Consultation-Liaison Psychiatry for older medical inpatients: The HOME Study RCT of its effectiveness and cost-effectiveness.

Sharpe M. et al, (2025), Health Soc Care Deliv Res, 13, 1 - 85

Social inequalities in the use of formal and informal home care in older women: evidence from a large UK cohort study.

Quinn M. et al, (2025), Age Ageing, 54

Delirium prevalence, diagnostic uncertainty and outcomes in ORCHARD-EPR: validation against prospective reference cohorts

PENDLEBURY S., (2025), Age and Ageing

Trends and variation in the incidence of hip fracture in England before, during, and after the COVID-19 pandemic (2014-2024): a population-based observational study

Webster J. et al, (2025), The Lancet Regional Health. Europe

Temporal trends in hospital-recorded pulmonary embolism in England before, during and after the COVID-19 pandemic (2008–2024): a population-based observational study

Zhong X. et al, (2025), The Lancet Regional Health. Europe

Barriers to and enablers of the early diagnosis of breast cancer among women from ethnic minority backgrounds in the UK: protocol for a qualitative evidence synthesis

SAJJAD P. et al, (2024), BMJ Open

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