Helen Dakin
Colleges
Helen Dakin
MSc DPhil
Associate Professor
Helen Dakin is a health economist specialising in assessing the cost-effectiveness of healthcare interventions. Her research interests include methods for trial and model-based economic evaluation, with particular focus on uncertainty, interacting healthcare decisions and factorial trials.
Helen co-leads the Patient Reported Outcomes and Health Economics module of the MSc in Clinical Trials and leads the Health Economics Research Centre (HERC) online short course Integrating Economic Evaluation into Clinical Trials.
Helen has led and collaborated on the health economic analyses of numerous randomised controlled trials, models and observational studies. Projects include: the KAT trial, which assesses the cost-effectiveness of different types of knee replacement component; the STAR trial, which evaluates radiotherapy alongside ranibizumab (Lucentis) in age-related macular degeneration; and the Supporting Women with adhErence to adjuvant Endocrine Therapy following breast cancer (SWEET) trial.
Helen joined HERC in February 2008. In 2014, she completed a DPhil at the University of Oxford on the optimal methods for conducting economic evaluations of factorial clinical trials. She previously worked at Abacus International and completed her MSc in Economic Evaluation in Healthcare at City University. She graduated from Cambridge University with Masters and Bachelor's degrees in Biochemistry.
Key publications
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Using QALYs as an outcome for assessing global prediction accuracy in diabetes simulation models
DAKIN H. et al, (2024), Medical decision making
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Cost-effectiveness of a lidocaine 5% medicated plaster relative to gabapentin for postherpetic neuralgia in the United Kingdom
Dakin HA. et al, (2007), Clin Ther, 29, 1491 - 1507
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Lifetime cost-effectiveness simulation of once-weekly exenatide in type 2 diabetes: A cost-utility analysis based on the EXSCEL trial.
Becker F. et al, (2022), Diabetes Res Clin Pract, 183
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Mapping analyses to estimate EQ-5D utilities and responses based on Oxford Knee Score
Dakin H. et al, (2012), Quality of Life Research, 1 - 12
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The use of patient-reported outcome measures to guide referral for hip and knee replacement: Part 2 – a cost-effectiveness analysis
DAKIN H. et al, (2020), Bone and Joint Journal
Recent publications
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MSR176 Q-Squared as a Mapping Model Performance Metric in Gastrointestinal Disease
Mallon K. et al, (2025), Value in Health, 28
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MSR199 The HERC Database of Mapping Studies: A 2025 Update of a Live Systematic Review of Studies Predicting EQ-5D From Other Patient-Reported Outcome Measures
Mallon K. et al, (2025), Value in Health, 28, s534 - s535
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Improving outcomeS for Women diagnosed with early breast cancer through adhErence to adjuvant Endocrine Therapy (SWEET): study protocol for a pragmatic Randomised Control Trial of a patient-centred intervention to improve adherence to endocrine therapy in early breast cancer
Mcgeagh L. et al, (2025), Trials
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HERC database of mapping studies, Version 10.0
DAKIN H. et al, (2025)
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Supporting women with adherence to adjuvant endocrine therapy (SWEET): feasibility study of the HT&Me intervention.
McGeagh L. et al, (2025), Eur J Oncol Nurs, 80