Dr David Smith
David Smith
MSc, PhD
Senior Researcher
David joined the Health Economics Research Centre (HERC) as a senior researcher in February 2023.
His current research involves the development of health-economic models to evaluate the efficiency of infectious disease surveillance and control interventions, with a focus on antimicrobial resistance, Covid-19 and healthcare-associated infections.
David is particularly interested in using transmission modelling within health-economic evaluations to inform intervention design, including the optimisation of SARS-CoV-2 surveillance programmes and the setting of reduction targets for inappropriate antibiotic prescribing.
Prior to joining HERC, David was based at Institut Pasteur in France, where he used transmission modelling to study various topics in nosocomial infection control, including how antibiotic-induced microbiome dysbiosis impacts bacterial transmission, how testing strategies can be optimised for Covid-19 prevention, and how Covid-19 outbreaks influence the spread of antibiotic-resistant bacteria.
Previously, David worked as a mathematical modeller at Public Health England, and was involved in projects including national evaluations of inappropriate antibiotic prescribing in English primary care, and of the health-economic burden of urinary catheter-associated infection in English hospitals.
David holds a PhD in public health and biostatistics from Université Paris-Saclay, and an MSc in ecology and evolutionary biology from the University of Toronto.
Recent publications
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Impacts of the COVID-19 pandemic on antibiotic use and resistance in hospitals: a retrospective ecological analysis of French national surveillance data over 2019-2022
Layan M. et al, (2024)
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Health and economic impacts of Lassa vaccination campaigns in West Africa
Smith D. et al, (2024), Nature Medicine
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Climate change, malaria and neglected tropical diseases: a scoping review.
Klepac P. et al, (2024), Trans R Soc Trop Med Hyg
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Antimicrobial Resistance as Risk Factor for Recurrent Bacteremia after Staphylococcus aureus, Escherichia coli, or Klebsiella spp. Community-Onset Bacteremia.
Abbara S. et al, (2024), Emerg Infect Dis, 30, 974 - 983
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Exploring factors shaping antibiotic resistance patterns in Streptococcus pneumoniae during the 2020 COVID-19 pandemic
Kovacevic A. et al, (2024), eLife, 13